Novel benzamide compounds including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating coagulation disorders.
申请公布号
EP1259485(B1)
申请公布日期
2005.11.30
申请号
EP20010918257
申请日期
2001.02.28
申请人
MILLENNIUM PHARMACEUTICALS, INC.
发明人
ZHU, BING-YAN;ZHANG, PENGLIE;WANG, LINGYAN;HUANG, WENRONG;GOLDMAN, ERICK;LI, WENHAO;ZUCKETT, JINGMEI;SONG, YONGHONG;SCARBOROUGH, ROBERT