QUATERNARY SALTS OF N-SUBSTITUTED CYCLIC OR ACYCLIC AMINES AS PHARMACEUTICALS

摘要

In one aspect, the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment and/or prevention of cough in warm-blooded animals, including humans, such as compounds of the following formula (I): Y- J -E An- wherein J is independently selected from a group represented by one of formulae (II), (III) and (IV).