| 发明名称 |
CYCLOALKYL INHIBITORS OF POTASSIUM CHANNEL FUNCTION |
| 摘要 |
Novel cycloalkyl compounds useful as inhibitors of potassium channel function (especially inhibitors of the K v l subfamily of voltage gated K + channels, especially inhibitors K v 1.5 which has been linked to the ultra-rapidly activating delayed rectifier K + current I Kur ), methods of using such compounds in the prevention and treatment of arrhythmia and I Kur -associated conditions, and pharmaceutical compositions containing such compounds. |
| 申请公布号 |
PL375359(A1) |
申请公布日期 |
2005.11.28 |
| 申请号 |
PL20030375359 |
申请日期 |
2003.01.31 |
| 申请人 |
BRISTOL-MYERS SQUIBB CO.;ICAGEN,INC. |
发明人 |
LLOYD JOHN;JEON YOON T.;FINLAY HEATHER;YAN LIN;GROSS MICHAEL F.;BEAUDOIN SERGE |
| 分类号 |
A61K;A61K45/06;C07C233/58;C07C233/59;C07C233/60;C07C233/65;C07C235/06;C07C235/34;C07C235/46;C07C235/60;C07C279/16;C07C279/24;C07C279/28;C07C307/02;C07C307/04;C07C307/08;C07C307/10;C07C311/16;C07C311/29;C07C311/55;C07C311/59;C07C311/64;C07C323/62;C07D213/40;C07D213/69;C07D213/82;C07D217/22;C07D233/48;C07D233/54;C07D233/76;C07D235/10;C07D235/14;C07D239/42;C07D239/94;C07D239/95;C07D241/06;C07D249/04;C07D251/44;C07D251/46;C07D261/08;C07D261/14;C07D271/06;C07D295/13;C07D295/185;C07D295/215;C07D295/26;C07D307/68;C07D309/04;C07D309/08;C07D333/20;C07D333/28;C07D333/38;C07D333/58;C07D333/62;C07D409/12;C07D413/12;C07D471/04;C07D487/04;C07D521/00 |
主分类号 |
A61K |
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