发明名称 AMINOALCOHOL DERIVATIVES
摘要 The present invention relates to a compound formula [I]: wherein ect., X is bond, -CH2-, etc., Y is bond, -O-(CH2)n- (in which n is 1, 2, 3 or 4), etc., Z is cyano, tetrazolyl, etc., R1 is hydrogen, lower alkyl, etc., R2 is hydrogen or an amino protective group, R3 is hydrogen or lower alkyl, R4 is hydrogen or lower alkyl, R5 and R8 are each independently hydrogen, halogen, hydroxy, lower alkyl, etc., R6 is hydrogen, lower alkyl, etc., R9 is hydrogen or lower alkyl, and i is 1 or 2, or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.
申请公布号 PL375195(A1) 申请公布日期 2005.11.28
申请号 PL20030375195 申请日期 2003.06.25
申请人 ASTELLAS PHARMA INC. 发明人 HATTORI KOUJI;TOMISHIMA YASUYO;IMANISHI MASASHI
分类号 C07D333/40;A61K31/137;A61K31/195;A61K31/235;A61K31/352;A61K31/381;A61K31/44;A61K31/4406;A61K31/455;A61K31/603;A61P13/02;A61P43/00;C07C213/00;C07C215/28;C07C215/52;C07C217/60;C07C217/92;C07C227/20;C07C229/00;C07C229/36;C07C229/38;C07C255/58;C07C269/06;C07C271/16;C07C271/22;C07C315/02;C07C317/50;C07C319/20;C07C323/32;C07C323/43;C07C323/63;C07D213/38;C07D213/40;C07D213/61;C07D213/80;C07D295/135;C07D295/155;C07D311/78 主分类号 C07D333/40
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