摘要 |
A bispecific antibody comprising two antibody variable domains on a single polypeptide chain, wherein a first portion of the bispecific antibody is capable of recruiting the activity of a human immune effector cell by specifically binding to an effector antigen on the human immune effector cell, said first portion consisting of one antibody variable domain, and a second portion of the bispecific antibody specifically binds to a target antigen other than the effector antigen, said target antigen on a target cell other than said human immune effector cell, and said second portion comprising one antibody variable domain. |
申请人 |
MICROMET AG;KUFER, PETER;BERRY, MERRY;BAEUERLE, PATRICK;ITIN, CHRISTIAN |
发明人 |
KUFER, PETER;BERRY, MERRY;BAEUERLE, PATRICK;ITIN, CHRISTIAN |