发明名称 |
BIOLOGICAL MOLECULE-REACTIVE HYDROPHILIC SILICONE SURFACE |
摘要 |
<p>A silicone polymer having a modified surface is described, wherein said modification consists of a covalently attached water soluble polymer bearing an activating group, wherein said activating group reacts with reactive functionalities on one or more biological molecules so that said one or more biological molecules become covalently attached to said silicone polymer. The modified silicones are reacted with biological molecules to make them more biocompatible for use in biodiagnostic, biosensor or bioaffinity applications, or for coatings for in vivo transplantation or for liners exposed to biological broths.</p> |
申请公布号 |
WO2005111116(A1) |
申请公布日期 |
2005.11.24 |
申请号 |
WO2005CA00739 |
申请日期 |
2005.05.17 |
申请人 |
MCMASTER UNIVERSITY;BROOK, MICHAEL, A.;SHEARDOWN, HEATHER;CHEN, HONG |
发明人 |
BROOK, MICHAEL, A.;SHEARDOWN, HEATHER;CHEN, HONG |
分类号 |
C07C69/02;C07D207/46;C08G65/332;C08G65/336;C08G77/38;C08G77/42;C08G77/46;(IPC1-7):C08G77/42 |
主分类号 |
C07C69/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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