发明名称 Substituted alkylamine derivatives and methods of use
摘要 Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
申请公布号 US2005261313(A1) 申请公布日期 2005.11.24
申请号 US20040014184 申请日期 2004.12.15
申请人 AMGEN INC. 发明人 ASKEW BENNY;ADAMS JEFFREY;BOOKER SHON;CHEN GUOQING;DIPIETRO LUCIAN V.;ELBAUM DANIEL;GERMAIN JULIE;GEUNS-MEYER STEPHANIE D.;HABGOOD GREGORY J.;HANDLEY MICHAEL;HUANG QI;KIM TAE-SEONG;LI AIWEN;NISHIMURA NOBUKO;NOMAK RANA;PATEL VINOD F.;RIAHI BABAK;KIM JOSEPH L.;XI NING;YANG KEVIN;YUAN CHESTER C.
分类号 A61K31/4436;A61K31/4439;A61K31/444;A61K31/4709;A61K31/496;A61K31/501;A61K31/506;A61K31/5377;A61P9/10;A61P11/06;A61P15/08;A61P17/06;A61P19/00;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D213/82;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D407/14;C07D409/04;C07D409/12;C07D409/14;C07D413/14;C07D417/14;C07D471/02;C07D471/04;C07D491/02;(IPC1-7):C07D491/02;C07D43/02;C07D41/02;A61K31/470;A61K31/443 主分类号 A61K31/4436
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