Compositions and methods for treatment of ulcerative colitis

摘要

The present invention relates to the identification of TCP-1 gamma as a protein whose expression is decreased in patients with ulcerative colitis and Crohn's disease. This protein interacts with hTM5, which is involved in the pathogenesis of ulcerative colitis. Compositions and methods for diagnosis and treatment, including methods for following up the efficacy of treatment of ulcerative colitis are provided.