Co-encapsulated WT1 polypeptide and immunostimulant microsphere formulations and methods thereof

摘要

Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise one or more of a WT1 WT1 polypeptides in combination with one or more immunostimulants, either independently or co-encapsulated with biodegradable polymeric microspheres. Such compositions may be used, for example, for the prevention and treatment of metastatic diseases.