| 摘要 |
Compounds of formula (I): see formula (I); wherein: X1 represents an atom or group selected from CR4aR4b, O, S(O)q1 and NR5, wherein R4a and R4b, which may be identical or different, each represent hydrogen or linear or branched C1-C6alkyl, or R4a and R4b, together with the carbon atom carrying them, form a C3-C7cycloalkyl group, q1 represents zero, 1 or 2, and R5 represents hydrogen or linear or branched C1-C6alkyl optionally substituted by hydroxy, m1 represents zero or an integer from 1 to 4 inclusive, m2 represents an integer from 1 to 4 inclusive, n1 and n2, which may be identical or different, each represent an integer from 1 to 3 inclusive, R1 represents hydrogen or a group selected from carboxy, linear or branched C1-C6alkoxycarbonyl, carbamoyl optionally substituted by 1 or 2 linear or branched C1-C6alkyl, and linear or branched C1-C6alkyl optionally substituted by hydroxy or by amino optionally substituted by 1 or 2 linear or branched C1-C6alkyl, R2 represents hydrogen or li near or branched C1-C6alkyl, Ak represents a linear or branched C1-C4alkylene chain optionally substituted by one or more halogen atoms, p represents zero, 1 or 2, R3 represents hydrogen or cyano, X2 and X3, which may be identical or different, each represent S(O)q2, wherein q2 represents zero, 1 or 2, or CR6aR6b, wherein R6a and R6b, which may be identical or different, each represent hydrogen or halogen, or R6a represents hydrogen and R6b represents hydroxy, its isomers and addition salts thereof with a pharmaceutically acceptable acid.
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