METHOD FOR EXPRESSING BIOSYNTHETIC PATHWAYS AND USES THEREOF

摘要

The invention pertains to a method of biosynthetically producing heterologous compounds in Rhodococci, including the steps of identifying genes which are involved in the biosynthesis of the desired compound, cloning the genes into an integrative vector, transferring the vector into Rhodococci, growing the Rhodococci to express the genes, and isolating the desired compound from the Rhodococci. The genes can be biosynthetic genes for the heterologous compounds. The desired compounds can also be the gene products. Integrative vectors developed for other Actinomycetes can be used.