| 摘要 |
A compound represented by the following Formula I : <CHEM> wherein Z<1> is C or N; m<1> is 0 when Z<1> is N and m<1> is 1 when Z<1> is C; R<3> can form a bond with R<2> when Z<1> is C; A<1> is O, SO2, or CH2; n<1> is 0 or 1 when A<1> is O or SO2 and n<1> is an integer of 0 to 3 when A<1> is CH2; R<1> is a group selected from the group consisting of a condensed aromatic ring, a substituted condensed aromatic ring, carboxyl, alkoxycarbonyl, and <CHEM> wherein R<1><1> is H or OH, or R<1><1> can form a bond with R<2> when Z<1> is C and n<1> is O; R<1><2> and R<1><3> are independently phenyl, substituted phenyl, a heterocyclic ring, or a substituted heterocyclic ring, or R<1><2> and R<1><3> can form a condensed ring; R<2> is H when forming no bond with R<3> or R<1><1>; R<3> is H when forming no bond with R<2>; k<1> is an integer of 2 to 5; Y<1> is a group selected from the group consisting of O, S, SO, SO2, CH2, and <CHEM> wherein Z<2> is N or C; m<2> is 0 when Z<2> is N and m<2> is 1 when Z<2> is C; A<2> is O, SO2, or CH2; n<2> is 0 or 1 when A<2> is O or SO2; n<2> is an integer of 0 to 3 when A<2> is CH2; R<4> is a group selected from the group consisting of alkyl, phenyl, substituted phenyl, a heterocyclic ring, a substituted heterocyclic ring, -CO-R<4><1>, and <CHEM> wherein R<4><1> is a group selected from the group consisting of OH, alkoxy, amino, arylalkyloxy, substituted amino, arylalkenyl, and substituted arylalkenyl; R<4><2> is H or OH, or R<4><2> can form a bond with R<5> when Z<2> is C and n<2> is 0; R<4><3> and R<4><4> are independently phenyl, substituted phenyl, a heterocyclic ring, or a substituted heterocyclic ring; R<5> is H when forming no bond with R<4><2>; Y<2> is CH2 or CO; Y<3> is (CH2)2 or phenylene; and k<2> is 0 or 1, or pharmaceutically acceptable salts thereof. |
