| 摘要 |
A compound having Formula (I) or Formula (II) is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R<1>, R<2>, R<3>, R<4>, and R<5>, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed. |
| 申请人 |
ABBOTT LABORATORIES;CARROLL, WILLIAM, A.;PEREZ-MEDRANO, ARTURO;FLORJANCIC, ALAN, S.;NELSON, DEREK, W.;PEDDI, SRIDHAR;LI, TONGMEI;BUNNELLE, ERIC, M.;HIRST, GAVIN, C.;LI, BIQIN |
发明人 |
CARROLL, WILLIAM, A.;PEREZ-MEDRANO, ARTURO;FLORJANCIC, ALAN, S.;NELSON, DEREK, W.;PEDDI, SRIDHAR;BUNNELLE, ERIC, M.;HIRST, GAVIN, C.;LI, BIQIN |
