发明名称 |
Treatment of insulin resistance syndrome and type 2 diabetes with PDE9 inhibitors |
摘要 |
This invention is directed to a method of treating insulin resistance syndrome (IRS), hypertension and/or type 2 diabetes in a mammal comprising administering to said mammal a cGMP PDE9 inhibitor or a pharmaceutical composition thereof. This invention is also directed to such methods wherein said cGMP PDE9 inhibitor is used in combination with other agents to treat IRS, hypertension and/or type 2 diabetes.
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申请公布号 |
US6967204(B2) |
申请公布日期 |
2005.11.22 |
申请号 |
US20020283814 |
申请日期 |
2002.10.29 |
申请人 |
PFIZER INC |
发明人 |
FRYBURG DAVID A.;GIBBS EARL MICHAEL |
分类号 |
C07D487/04;A61K31/437;A61K31/505;A61K31/519;A61K31/5377;A61K31/541;A61K45/00;A61K45/06;A61P3/04;A61P3/06;A61P3/08;A61P3/10;A61P5/50;A61P7/02;A61P9/10;A61P9/12;A61P19/06;A61P43/00;(IPC1-7):A61K31/52 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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