发明名称 |
Prolonged release microspheres for injectable administration |
摘要 |
The present invention provides microspheres intended to be administered by injection comprising a protein active ingredient and an agent coating the active ingredient intended to prolong its release, wherein they are free of any trace of organic solvent and they can be obtained according to a coating method involving bringing the active ingredient and the coating agent into contact, with stirring, in a supercritical fluid, said coating agent being soluble in this supercritical fluid. |
申请公布号 |
US6967028(B2) |
申请公布日期 |
2005.11.22 |
申请号 |
US20010873271 |
申请日期 |
2001.06.05 |
申请人 |
LABORATOIRES DES PRODUITS ETHIQUES ETHYPHARM |
发明人 |
DULIEU CLAIRE;RICHARD JOEL;BENOIT JEAN-PIERRE |
分类号 |
A61K9/00;A61K9/16;(IPC1-7):A61K9/50;B32B15/02 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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