| 摘要 |
FIELD: medicine, vaccines. ^ SUBSTANCE: invention relates to a method for producing the combined vaccine comprising antigens of diphtheria, tetanus, whooping cough and hepatitis B. method involves stages of independent adsorption of each protective antigen on aluminum hydroxide used as a gel-adsorbent to different antigens: diphtheria, tetanus, whooping cough and hepatitis B followed by mixing adsorbed antigens. Advantage of invention involves the development of a method providing the improved evaluation and prophylaxis of adverse effect. ^ EFFECT: improved producing method. ^ 11 cl, 3 dwg, 1 tbl, 10 ex |
