| 发明名称 |
COMPOUND FOR INHIBITING INTERLEUKIN-1beta PROTEASE |
| 摘要 |
PROBLEM TO BE SOLVED: To obtain a compound and a composition for inhibiting interleukin-1β-protease activity and to provide a method for inhibiting interleukin-1β-protease activity. SOLUTION: The compound is represented by formula (1). For example, N-benzyloxycarbonyl-L-aspartic acid 2,6-dichlorobenzoyloxymethyl ketone is exemplified as the compound. COPYRIGHT: (C)2006,JPO&NCIPI
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| 申请公布号 |
JP2005320327(A) |
申请公布日期 |
2005.11.17 |
| 申请号 |
JP20050121492 |
申请日期 |
2005.04.19 |
| 申请人 |
VERTEX PHARMACEUT INC |
发明人 |
DOLLE ROLAND E;OSIFO IRENNEGBE K;SCHMIDT STANLEY J;HOYER DENTON W;ROSS TINA MORGAN;CHATURVEDULA PRASAD V;PROUTY CATHERINE P;AWAD MOHAMED M A;SALVINO JOSEPH M;RINKER JAMES M;LODGE ERIC P;SINGH JASBIR;ATOR MARK A |
| 分类号 |
A61K31/165;A61K31/17;A61K31/215;A61K31/235;A61K31/24;A61K31/27;A61K31/34;A61K31/341;A61K31/365;A61K31/38;A61K31/381;A61K31/445;A61K31/47;A61K31/472;A61K31/535;A61K31/5375;A61K31/54;A61K38/00;A61K38/55;A61P1/00;A61P1/16;A61P11/00;A61P19/00;A61P19/02;A61P25/00;A61P29/00;A61P31/04;A61P35/00;A61P37/00;A61P37/06;A61P43/00;C07C229/22;C07C233/51;C07C235/12;C07C237/08;C07C237/22;C07C237/36;C07C271/22;C07C275/16;C07C311/16;C07C311/19;C07D209/42;C07D209/44;C07D211/60;C07D215/48;C07D217/26;C07D223/06;C07D233/54;C07D233/64;C07D233/70;C07D233/88;C07D295/08;C07D295/092;C07D295/22;C07D295/30;C07D307/33;C07D307/68;C07D333/24;C07D333/36;C07D333/38;C07D453/02;C07K5/04;C07K5/06;C07K5/08;C07K14/81;C12N9/99;(IPC1-7):C07C271/22;A61K31/537 |
主分类号 |
A61K31/165 |
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