发明名称 |
METHODS AND COMPOSITIONS FOR REDUCING VIRAL GENOME AMOUNTS IN A TARGET CELL |
摘要 |
Methods and compositions for reducing viral genome amounts in a target cell are provided. In the subject methods, the activity of a miRNA is inhibited in a manner sufficient to reduce the amount of viral genome in the target cell, e.g., by introducing a miRNA inhibitory agent in the target cell. Also provided are pharmaceutical compositions, kits and systems for use in practicing the subject methods. The subject invention finds use in a variety of applications, including the treatment of subjects suffering from a viral mediated disease condition, e.g., an HCV mediated disease condition. |
申请公布号 |
WO2005107816(A2) |
申请公布日期 |
2005.11.17 |
申请号 |
WO2005US15264 |
申请日期 |
2005.05.03 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;SARNOW, PETER;JOPLING, CATHERINE, L.;LANCASTER, ALISSA, M. |
发明人 |
SARNOW, PETER;JOPLING, CATHERINE, L.;LANCASTER, ALISSA, M. |
分类号 |
A61K48/00;C12N15/11;C12N15/113 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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