MODULATION OF LYSOPHOSPHATIDYLCHOLINE AND TREATMENT OF DIET-INDUCED CONDITIONS

摘要

The present invention provides methods for the treatment of lysophosphatidylcholine-related conditions. In particular, the invention provides a method of treating an insulin-related condition, e.g., diabetes or diabetes type 2, and/or a weight-related-condition, e.g., unwanted weight gain or obesity, in an animal subject by reducing production, absorption and/or activity of lysophosphatidylcholine. Further, the beneficial effects of reducing lysophosphatidylcholine in terms of diabetes and weight gain are disclosed.