发明名称 |
PERFLUOROCARBON-SOLUBLE COMPOUNDS |
摘要 |
<p>The invention describes syntheses and purifications of several perfluorocarbon-soluble compounds having a general formula RF - L - X or RF - L - X - L - RF, wherein RF is a perfluorocarbon group, X is a hydrophilic moiety, and L is an amide linkage of general structure -CO-NH-. The invention also provides microemulsions comprising a PFC forming an oil phase, water or aqueous solution forming a water phase, and a PEG-based fluorosurfactant with an HFB (hydrophilic groups to fluorophilic groups balance) value from about 7 to about 13. The invention also provides a method of amidification of a fluorocompound. The method involves mixing perfluoracid chloride of a general formula CnF2n+1COCI with a compound containing an amine group with a general structure R-NH2 under reaction conditions sufficient to obtain a product having a general formula CnF2n+1-CONH-R.</p> |
申请公布号 |
WO2005107764(A1) |
申请公布日期 |
2005.11.17 |
申请号 |
WO2005US15348 |
申请日期 |
2005.05.02 |
申请人 |
UNIVERSITY OF SOUTHERN CALIFORNIA;PENG, CHING-AN;HSU, YU-CHIH |
发明人 |
PENG, CHING-AN;HSU, YU-CHIH |
分类号 |
A61K9/107;A61K31/56;C11D1/00;(IPC1-7):A61K31/56 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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