发明名称 |
ENGINEERED TUBULAR TISSUE STRUCTURES |
摘要 |
<p>A method and apparatus and associated components are described for producing a cellular tissue structure comprising a wall surrounding a space or passage. A suspension of cells is introduced into a culture vessel (70) of elongate tubular form defining an internal tissue formation surface. The vessel is rotated about a rotary axis to cause the cells in the suspension to move under the influence of centrifugal force to collect and form a layer on the tissue formation surface. The layer is then exposed to a tissue culture medium. The tissue formation surface is preferably resiliently compressive and a pulsed or other time-varying pressure is preferably applied during at least the maturation phase of formation of the cellular tissue structure. Various forms of apparatus are described to allow a large array of elongate culture vessels to be built and serviced in common or individually.</p> |
申请公布号 |
WO2005107642(A1) |
申请公布日期 |
2005.11.17 |
申请号 |
WO2005GB01740 |
申请日期 |
2005.05.09 |
申请人 |
UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED;JONES, DEREK, LEIGH |
发明人 |
JONES, DEREK, LEIGH |
分类号 |
A61F2/06;B04B5/00;C12M3/00;C12M3/06;(IPC1-7):A61F2/06 |
主分类号 |
A61F2/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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