| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for accurately and simply testing androgenic activity as much as possible. SOLUTION: This method for testing the androgenic activity possessed by a chemical substance has (1) a first step for measuring an expression level of a gene, etc., having a specific base sequence in a specimen derived from a mammalian which is preliminarily brought into contact with the chemical substance and (2) a second step for comparing a measured value of the expression level of the gene in the specimen obtained in the first step with a control value of the expression level of the gene, and then evaluating existence or nonexistence of the androgenic activity possessed by the chemical substance in the specimen, or a degree of generation of the activity, based on a difference between the values. COPYRIGHT: (C)2006,JPO&NCIPI
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