发明名称 Mage C2 antigenic peptides and uses thereof
摘要 This invention relates to isolated peptides derived from MAGE-C2, nucleic acid molecules that encode MAGE-C2 and the isolated peptides derived from MAGE-C2, expression vectors comprising the nucleic acid molecules, host cells transformed or transfected with the nucleic acid molecules or the expression vectors, and to tetramers comprising the peptides, HLA molecules, beta<SUB>2 </SUB>microglobulin and a first and second binding partner. This invention also relates to methods for using the peptides, nucleic acid molecules, expression vectors, tetramers and complexes of this invention as well as to cytolytic T cells which recognize the peptides in complex with an HLA molecule.
申请公布号 US2005255553(A1) 申请公布日期 2005.11.17
申请号 US20050044051 申请日期 2005.01.28
申请人 LUDWIG INSTITUTE OF CANCER RESEARCH 发明人 PEL ALINE V.;GODELAINE DANIELE;CARRASCO JAVIER;BRASSEUR FRANCIS;BOON-FALLEUR THIERRY
分类号 A61K38/00;A61K38/10;C07H21/04;C07K14/47;C12N15/09;C12P21/06;(IPC1-7):A61K38/10 主分类号 A61K38/00
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