发明名称 |
4-Amino-thieno[3,2-c]pyridine-7-carboxylic acid amides |
摘要 |
Disclosed are novel 4-amino-thieno[3,2-c]pyridine-7-carboxylic acid amides, and their pharmaceutically acceptable salts and esters, that are selective inhibitors of KDR and/or FGFR kinases. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular solid cancerous tumors of the breast, colon, lung and prostate. Also disclosed are pharmaceutical compositions containing these compounds and methods of treating cancer using these compounds.
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申请公布号 |
US2005256154(A1) |
申请公布日期 |
2005.11.17 |
申请号 |
US20050110614 |
申请日期 |
2005.04.20 |
申请人 |
LUK KIN-CHUN;MCDERMOTT LEE A;ROSSMAN PAMELA L;WOVKULICH PETER M;ZHANG ZHUMING |
发明人 |
LUK KIN-CHUN;MCDERMOTT LEE A.;ROSSMAN PAMELA L.;WOVKULICH PETER M.;ZHANG ZHUMING |
分类号 |
A61K31/4743;C07D498/02;(IPC1-7):A61K31/474 |
主分类号 |
A61K31/4743 |
代理机构 |
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