| 摘要 |
<p num="1"><br/><br/><br/>The present invention relates generally to a method for the generation of a <br/>substantially homogenous population of undifferentiated cells. More <br/>particularly, the present invention relates to a method for isolating a <br/>substantially homogenous population of stem cells, and in particular, mammary <br/>stem cells (MaSCs). The MaSCs of the present invention are isolated on the <br/>basis of differential levels of proteins present on their cell surface. The <br/>MaSCs of the present invention are particularly useful as targets for <br/>identifying agents which modulate MaSC survival, self-renewal, proliferation <br/>and/or differentiation in both normal and diseased tissue such as, but not <br/>limited to, tumor tissue, and, also as source of tissue for the regeneration, <br/>replacement and/or augmentation of tissue damaged and/or lost after disease or <br/>injury.<br/>
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