POLYMORPHISMS IN ABCB1 ASSOCIATED WITH A LACK OF CLINICAL RESPONSE TO MEDICAMENTS
摘要
The present invention relates to methods, compositions and kits for determining the prognosis of a clinical response in a human patient to a medicament which acts in the central nervous system and which is a substrate of the ABCB1 protein. Further, the invention relates to a combination of medicaments for the treatment of human patients having specific polymorphisms in the ABCB1 gene.
申请公布号
WO2005108605(A2)
申请公布日期
2005.11.17
申请号
WO2005EP05194
申请日期
2005.05.12
申请人
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN;UHR, MANFRED;HOLSBOER, FLORIAN;BINDER, ELISABETH;MUELLER-MYHSOK, BERTRAM