发明名称 |
PEPTIDE DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESSES FOR PREPARATION OF BOTH, AND USE THEREOF |
摘要 |
<p>The present invention provides a peptide derivative of formula (I) wherein X is -CHOH- or -CO-; R<SUP>1 </SUP>and R<SUP>2 </SUP>are hydrogen or substituted oxycarbonyl; R<SUP>3 </SUP>is substituted oxycarbonyl; R<SUP>4 </SUP>is hydroxyl, lower alkoxy, optionally substituted piperazinyl or the like; R<SUP>5 </SUP>is a R-group side chain of an alpha-amino acid optionally protected by a protective group, R<SUP>6 </SUP>is hydroxyl, lower alkoxy or the like; m is 0 or 1; and n is an integer of 2 to 6; or a pharmaceutically acceptable salt thereof. The present invention further provides a production process and use thereof.</p> |
申请公布号 |
EP1333024(A4) |
申请公布日期 |
2005.11.16 |
申请号 |
EP20010980959 |
申请日期 |
2001.11.02 |
申请人 |
TAIHO PHARMACEUTICAL CO., LTD. |
发明人 |
YAMAMOTO, KENJI;SUDA, YOSHIMITSU;ASAO, TETSUJI |
分类号 |
A61K38/00;A61P1/02;A61P43/00;C07C271/22;C07D295/185;C07K5/072;C07K5/093;(IPC1-7):C07C271/22;C07D295/18;C07K5/06;A61K31/27;A61K31/495;A61K38/06 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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