发明名称 |
ANTI-CD70 ANTIBODY-DRUG CONJUGATES AND THEIR USE FOR THE TREATMENT OF CANCER |
摘要 |
<p>Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic, immunosuppressive, or other therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the disclosed pharmaceutical compositions.</p> |
申请公布号 |
EP1594542(A2) |
申请公布日期 |
2005.11.16 |
申请号 |
EP20040713441 |
申请日期 |
2004.02.20 |
申请人 |
SEATTLE GENETICS, INC. |
发明人 |
LAW, CHE-LEUNG;WAHL, ALAN, F.;SCHOLLER, NATHALIE;PESTANO, LINDA, A. |
分类号 |
A61K47/48;A61K;A61K39/395;A61K49/00;A61P35/00;A61P37/00;C07K16/00;C07K16/28;(IPC1-7):A61K39/395 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|