发明名称 |
Methods for detecting nucleic acids indicative of cancer |
摘要 |
The invention provides methods for screening tissue or body fluid samples for nucleic acid indicia of cancer or precancer. Method are provided for screening a patient for cancer or precancer by detecting the presence of nucleic acid fragments that are longer than nucleic acid fragments expected to be present in a sample obtained from a healthy individual. In one embodiment, a positive screen for cancer or precancer is identified when a patient tissue or body fluid sample comprising exfoliated cells or cellular debris contains an amount of nucleic acid of a length greater than about 200 base pairs that exceeds a predetermined amount.
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申请公布号 |
US6964846(B1) |
申请公布日期 |
2005.11.15 |
申请号 |
US20000545162 |
申请日期 |
2000.04.07 |
申请人 |
EXACT SCIENCES CORPORATION |
发明人 |
SHUBER ANTHONY P. |
分类号 |
G01N33/50;C12N15/09;C12Q1/68;G01N33/574;(IPC1-7):C12P19/34 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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