| 发明名称 |
SUBSTITUIERTE ARYLPYRAZINE |
| 摘要 |
Arylpyrazine compounds are provided, including arylpyrazines that can bind with high affinity and high selectivity to CRF<SUB>1 </SUB>receptors, including human CRF<SUB>1 </SUB>receptors. The invention thus includes methods for treatment of disorders and diseases associated with CRF<SUB>1 </SUB>receptors, including CNS-related disorders and diseases, particularly affective disorders and diseases, and acute and chronic neurological disorders and diseases. |
| 申请公布号 |
AT307121(T) |
申请公布日期 |
2005.11.15 |
| 申请号 |
AT20010910939T |
申请日期 |
2001.02.16 |
| 申请人 |
NEUROGEN CORPORATION |
发明人 |
YOON, TAEYOUNG;GE, PING;HORVATH, RAYMOND, F.;DE LOMBAERT, STEPHANE;HODGETTS, KEVIN, J.;DOLLER, DARIO;ZHANG, CUNYU |
| 分类号 |
A61K31/4965;A61K31/5377;A61P1/00;A61P1/04;A61P9/10;A61P9/12;A61P15/00;A61P19/10;A61P25/00;A61P25/18;A61P25/22;A61P25/24;A61P43/00;C07D241/00;C07D241/12;C07D241/18;C07D241/20;C07D401/04;C07D401/12;C07D403/04;C07D403/12;C07D405/12;C07D409/04 |
主分类号 |
A61K31/4965 |
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