CD40 VARIANTS AND USES THEREOF

摘要

Disclosed are newly discovered CD40 variant molecules, their polypeptide sequences, and the polynucleotides encoding the polypeptide sequences. Also provided are procedures for producing such polypeptides by recombinant techniques employing, for example, vectors and host cells. Also disclosed are methods for utilizing such polypeptides and modulators thereof for the treatment of diseases, including cancer, immune diseases, infectious diseases, and ischemic diseases.