| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To solve the problem in which effective HCV antibody-measuring method is required from the viewpoint of effective utilization of donated blood, because a conventional HCV antibody-measuring method detects also HCV antibody of an HCV RNA-negative person and the blood of HCV RNA-negative person free from risk of secondary infection is also discarded in inspection of a donor specimen. <P>SOLUTION: In the HCV antibody-measuring method using HCV core antigen polypeptide, binding of the HCV antibody of an HCV RNA-positive person to an HCV core antigen polypeptide can be maintained while binding of the HCV antibody of an HCV RNA-negative person to the polypeptide is prevented by making a polypeptide composed of an amino acid sequence of a sequence No.2 or its partial fragment coexist in a reaction mixture. The present invention provides the polypeptide capable of efficiently excluding a sample derived from the HCV RNA-negative person and the HCV antibody-measuring method improved in specificity by using the peptide. <P>COPYRIGHT: (C)2006,JPO&NCIPI</p> |
