发明名称 Drugs for treating vascular diseases.
摘要 A medicament for prophylactic and/or therapeutic treatment of a vascular disease such as vascular restenosis and/or reocclusion after percutaneous transluminal coronary angioplasty using an intravascular stent, which comprises as an active ingredient a substance selected from the group consisting of retinoids and agents for controlling actions of retinoids such as 4-Ä5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoylÜbenzoic acid or a salt thereof, or 4-ÄÄÄ3,5-bis-(trimethylsilyl)phenylÜcarbonylÜaminoÜbenzoic acid or a salt thereof, wherein said substance has substantially no antiproliferative action on vascular endothelial cells, but substantially has antiproliferative action on vascular smooth muscle cells.
申请公布号 ZA200408744(B) 申请公布日期 2005.11.10
申请号 ZA20040008744 申请日期 2003.04.22
申请人 RESEARCH FOUNDATION ITSUU LABORATORY. 发明人 RYOZO NAGAI;TAKAYUKI SHINDO;ICHIRO MANABE;KOICHI SHUDO;HIROYUKI KAGECHIKA
分类号 A61K31/27;A61K31/695;A61L31/16;A61P9/00;A61P9/10;A61P9/14;A61P43/00 主分类号 A61K31/27
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