| 发明名称 |
2-AMINO- AND 2-THIO-SUBSTITUTED 1,3-DIAMINOPROPANES |
| 摘要 |
Disclosed are compounds of the formula: where variables Q, Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. |
| 申请公布号 |
WO2005095326(A3) |
申请公布日期 |
2005.11.10 |
| 申请号 |
WO2005US09920 |
申请日期 |
2005.03.25 |
| 申请人 |
ELAN PHARMACEUTICALS, INC.;PHARMACIA & UP JOHN COMPANY;HOM, ROY;TUCKER, JOHN;JOHN, VARGHESE;SHAH, NEERAV |
发明人 |
HOM, ROY;TUCKER, JOHN;JOHN, VARGHESE;SHAH, NEERAV |
| 分类号 |
A61K31/16;A61K31/353;A61K31/382;A61K31/47;C07C233/36;C07C235/10;C07C271/24;C07C311/05;C07C323/41;C07C327/42;C07D213/38;C07D215/38;C07D215/46;C07D303/36;C07D307/52;C07D311/68;C07D311/76;C07D317/72;C07D333/20;C07D335/04;C07D335/06;C07D405/04 |
主分类号 |
A61K31/16 |
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