| 摘要 |
The present invention provides an improved process for the preparation of 4-(4-Fluorobenzoyl)butyric acid of formula (I), which is prepared on a commercial scale using normal quality fluorobenzene (benzene content 300-700 ppm) with the desfluoro analogue impurity at an acceptable level (less than 0.1% by HPLC). The 4-(4-Fluorobenzoyl)butyric acid has the formula (I) is a key raw material for the synthesis of anti-hyperlipoproteinemetic drug ezetimibe.
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