VERFAHREN ZUR ERHÖHUNG DER PRODUKTION VON CLAVAM-ANTIBIOTIKA
摘要
<p>A process for increasing the amount of clavam produced by an organism having both a clavam pathway or a portion thereof and a cephalosporin pathway or a portion thereof by interfering with the conversion of L-lysine to L-alpha-aminoadipic acid in the cephalosporin pathway. Plasmids containing a defective LAT (lysine amino transferase) gene and organisms containing such plasmids are also provided.</p>
申请公布号
DE69633921(T2)
申请公布日期
2005.11.10
申请号
DE1996633921T
申请日期
1996.06.06
申请人
SMITHKLINE BEECHAM P.L.C., BRENTFORD;THE GOVERNORS OF THE UNIVERSITY OF ALBERTA, EDMONTON
发明人
HOLMS, HENRY;PARADKAR, ASHISH SUDHAKAR;MOSHER, ROY HENRY;JENSEN, DR.