发明名称 |
DIAGNOSTIC AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH PROTO-ONCOGENE TYROSINE-PROTEIN KINASE (FYN) |
摘要 |
The invention provides a human FYN which is associated with cardiovascular diseases, endocrinological diseases, metabolic diseases, gastroenterological diseases, inflammation, hematological diseases, respiratory diseases, neurological diseases and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, endocrinological diseases, metabolic diseases, gastroenterological diseases, inflammation, hematological diseases, respiratory diseases, neurological diseases and urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of FYN as well as pharmaceutical compositions comprising such compounds. |
申请公布号 |
WO2005083441(A3) |
申请公布日期 |
2005.11.10 |
申请号 |
WO2005EP01419 |
申请日期 |
2005.02.12 |
申请人 |
BAYER HEALTHCARE AG;GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS;THIELE, RALF;SUMMER, HOLGER |
发明人 |
GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS;THIELE, RALF;SUMMER, HOLGER |
分类号 |
A61K38/43;A61K38/45;C12Q1/48;C12Q1/68 |
主分类号 |
A61K38/43 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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