| 发明名称 |
Gene knock-down by intracellular expression of aptamers |
| 摘要 |
Materials and methods are provided for target validation by gene knock-down with intracellularly expressed aptamers and siRNAs. The aptamers produced by the materials and methods of the invention are useful in target validation for therapeutics development.
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| 申请公布号 |
US2005250106(A1) |
申请公布日期 |
2005.11.10 |
| 申请号 |
US20040831632 |
申请日期 |
2004.04.23 |
| 申请人 |
EPSTEIN DAVID;MARSH HAROLD N;PENDERGRAST SHANNON;THOMPSON KRISTIN |
发明人 |
EPSTEIN DAVID;MARSH HAROLD N.;PENDERGRAST SHANNON;THOMPSON KRISTIN |
| 分类号 |
A61K48/00;C07H21/02;C12N15/11;C12N15/113;C12N15/115;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
A61K48/00 |
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