THERMOSENSITIVE, BIOCOMPATIBLE POLYMER CARRIERS WITH A VARIABLE PHYSICAL STRUCTURE FOR TREATMENT, DIAGNOSIS AND ANALYSIS

摘要

The invention relates to biocompatible, thermosensitive polymers that can be heated by encapsulating magnetic and/or metallic colloids or magnetic nanoparticles by means of a high-frequency, magnetic alternating field. The inductive heating of the polymer matrix triggers physical structural changes in the polymer matrix, that lead to encapsulated bioactive substances being rapidly released in the polymer matrix. Said stimulus-response principle is used to produce controllable medicament depots, contrast-reinforcing means for NMR diagnosis, and manipulable microtools, as means for blocking blood vessels and as controllable porogens during the production of membranes.