发明名称 |
NITRIC OXIDE DONORS AND USES THEREOF |
摘要 |
<p>Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.</p> |
申请公布号 |
WO2005105765(A1) |
申请公布日期 |
2005.11.10 |
申请号 |
WO2005IL00481 |
申请日期 |
2005.05.05 |
申请人 |
RENOPHARM LTD.;ASSAF, PETER;GAZALEEN-MARIEE, ELHAM;NAVEH, MICHAEL |
发明人 |
ASSAF, PETER;GAZALEEN-MARIEE, ELHAM;NAVEH, MICHAEL |
分类号 |
A61K31/427;C07D277/22;C07D277/24;C07D277/34;C07D277/36;C07D277/42;C07D417/04;C07D417/06;C07D417/10;C07D417/12;C07D495/04;(IPC1-7):C07D277/24;A61K31/443;A61K31/426;C07D277/46;C07D277/50;C07D277/40 |
主分类号 |
A61K31/427 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|