发明名称 |
PROCESS FOR PREPARING CINNAMIC ACIDS AND ALKYL ESTERS THEREOF |
摘要 |
<p>A process for producing cinnamic acids and alkyl esters thereof, particularly, fluorinated cinnamic acids and alkyl esters thereof. The process comprises reacting the appropriate bromobenzene and acrylic acid ester in a palladium-catalyzed HECK reaction under JEFFREY conditions using a phase-transfer catalyst (PTC) and an organic base to produce the corresponding cinnamic acid ester, and then preferably hydrolyzing the resulting ester under appropriate basic conditions, e.g. in the presence of a hydroxide, and precipitating the corresponding cinnamic acid product.</p> |
申请公布号 |
WO2005105728(A1) |
申请公布日期 |
2005.11.10 |
申请号 |
WO2005US12676 |
申请日期 |
2005.04.14 |
申请人 |
HONEYWELL INTERNATIONAL INC.;WILKEN, JOERG;WASSMANN-WILKEN, SUZANNE;KANSCHIK-CONRADSEN, ANDREAS |
发明人 |
WILKEN, JOERG;WASSMANN-WILKEN, SUZANNE;KANSCHIK-CONRADSEN, ANDREAS |
分类号 |
C07C51/09;C07C67/343;(IPC1-7):C07C67/343;C07C57/44;C07C57/60;C07C69/618;C07C69/65 |
主分类号 |
C07C51/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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