| 摘要 |
<p>It is intended to avoid any possibility of error attributed to a nucleic acid used as a standard, a probe or probe spot, etc. or enable correction thereof, to analyze the frequency of gene expression with high reproducibility and to analyze any change of primary structure in a sample nucleic acid. There is provided a method of analyzing the primary structure of at least one target base sequence present in a sample nucleic acid by detecting any signal from a sample nucleic acid hybrid composed of a probe and the sample nucleic acid, wherein any signal from a synthetic standard nucleic acid hybrid composed of the probe and a synthetic standard nucleic acid containing the at least one target base sequence is detected and on the basis of the signal from the synthetic standard nucleic acid hybrid, the signal from the sample nucleic acid hybrid is corrected to thereby effect analysis of the primary structure of the sample nucleic acid.</p> |
