| 摘要 |
FIELD: biotechnology, immunology, in particular production of serum panels to control quality of test systems for lues serotological diagnosis. ^ SUBSTANCE: claimed panel contains set of samples with standardized content of IgG class antibodies to T. palladium p17 and p41 antigens: namely sample with prevalent content of antibodies to p17 antigen, samples with prevalent content of antibodies to p41 antigen, samples containing antibodies to p17 antigen only, samples containing antibodies to p41 antigen only, and samples containing mixture antibodies to h17 and p41 in equal concentrations. Claimed method includes sampling of positive serums based on ratio (K) of reverse titers of antibodies to T. palladium antigens with mol.w. of 17 and 41 kD (K = T-1 p17/T-1 p41) and sampling of original serum samples with K>=2, K<=1|2 and K = 1. Said samples are diluted with non-immune donated serum to produce necessary concentration of specific antibodies. ^ EFFECT: improved method for examination of test system specificity, sensitivity, and other characteristics. ^ 7 cl, 2 tbl, 6 ex |
