摘要 |
PROBLEM TO BE SOLVED: To provide an improved method for producing an N-acylamino acid which is advantageous costwise and facilitates the operation procedure in the amidocarbonyl reaction using an aldehyde compound, an amide compound, a palladium catalyst, and carbon monoxide. SOLUTION: The method for efficiently producing an N-acylamino acid comprises reacting an aldehyde compound and an amide compound with carbon monoxide in the presence of a palladium catalyst and a halogenoacid such as hydrobromic acid. COPYRIGHT: (C)2006,JPO&NCIPI
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