DIASTEREOSELECTIVE ADDITION OF LITHIATED N-METHYLIMIDAZOLE ON SULFINIMINES
摘要
<p>A diastereoselective synthesis process for the preparation of (R)-(+)- 6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl2(1H)-quinolinone which comprises the preparation of a compound of formula (VIII) and the stereochemically isomeric forms thereof wherein R is C1-6alkyl or C1-6alkylphenyl-.</p>
