Polymorphisms in TH CLCN7 gene as genetic markers for bone mass

摘要

Provided are genetic methods and materials for assessing bone mineral density (BMD)and determining the susceptibility of an individual to a disorder which is associated witha low level of BMD, the method comprising use of chloride channel 7 (Clcn7) marker.The methods may be used e.g. for diagnosis of osteoporosis. Preferred Clcn7 markers at specified positions are disclosed.