| 发明名称 |
3-HYDROXY GAMMA-LACTONE BASED ENANTIOSELECTIVE SYNTHESIS OF AZETIDINONES |
| 摘要 |
The invention relates to a process for producing a compound of formula (I) wherein R1, R2 and R3 are as defined in the specification, which comprises reacting a lactone with an imine to obtain a chiral diol of formul a (IV) oxidizing the diol, condensing the resultant aldehyde with an enolether , hydrogenating the product, and chirally catalytically reducing the resultant ketone.
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| 申请公布号 |
CA2255662(C) |
申请公布日期 |
2005.11.08 |
| 申请号 |
CA19972255662 |
申请日期 |
1997.05.28 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
CHEN, XING;WONG, YEE-SHING;STEINMAN, MARTIN;SCHUMACHER, DORIS P.;WU, GUANG-ZHONG |
| 分类号 |
C07D205/08;(IPC1-7):C07D205/08;C07D401/00;C07D403/00;C07D405/00;C07D409/00;C07D413/00 |
主分类号 |
C07D205/08 |
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