发明名称 |
Antibacterial and antiviral agents and methods of screening for the same |
摘要 |
A method of screening for compounds useful for inhibiting retrovirus propagation in a host for the retrovirus, wherein the retrovirus primes reverse transcription in the host by binding of a specific host tRNA to retrovirus RNA at at least a pair of separate binding sites on the host tRNA, comprises contacting the specific host tRNA to the retrovirus RNA in the presence of the test compound, and then determining whether the compound inhibits the binding of the specific host tRNA to the retrovirus RNA in the presence of the test compound.
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申请公布号 |
US6962785(B2) |
申请公布日期 |
2005.11.08 |
申请号 |
US20020212905 |
申请日期 |
2002.08.06 |
申请人 |
NORTH CAROLINA STATE UNIVERSITY |
发明人 |
AGRIS PAUL F.;ASHRAF SALMAN |
分类号 |
C12Q1/18;C12Q1/68;(IPC1-7):C12Q1/68;C07H21/02;C07H21/04 |
主分类号 |
C12Q1/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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