发明名称 PROCESS FOR PREPARATION OF PHENETHYLAMINE DERIVATIVES
摘要 A process for the preparation of a compound of formula (I), wherein R1, and R2 are ortho or para substituents, independently selected from the group consisting of hydrogen, hydroxyl, C1-C6 alkyl, C1-C6 alkoxy, C7-C9 aralkoxy, C2-C7 alkanoyloxy, C1-C6 alkylmercapto, halo and trifluoromethyl; R3 is hydrogen or C1-C6 alkyl; R4 is hydrogen, C1-C6 alkyl, formyl or C 2-C7 alkanoyl; n is one of the integers 0, 1, 2, 3 or 4; and the dotted line represents optional olefinic unsaturation; comprising hydrogenating a compound of formula (III), in the presence of a nickel or cobalt catalyst at a temperature of about 5°C to 25°C.
申请公布号 KR20050106102(A) 申请公布日期 2005.11.08
申请号 KR20057016854 申请日期 2005.09.09
申请人 WYETH 发明人 KIM, KEUN SIK;KIM, KWANG IL;CHAI, KI BYUNG
分类号 C07C213/02;C07C215/42;C07C217/74;(IPC1-7):C07C213/02;C07C217/14 主分类号 C07C213/02
代理机构 代理人
主权项
地址