| 摘要 |
The invention relates to pharmaceutical and cosmetic formulation, especially to liposomes containing asiaticoside and the uses in preparation of pharmaceuticals and cosmetics. According to the invention, asiaticoside is located between lipids bilayer of the liosomes, forming hydrophilic asiaticoside limposomes by melting asiaticoside and lipids with heat or dissolving them in organic solvent(s), evaporating solvent(s) with rotatory evaporatoprs, adding water thereto, vibrating, preparing dispersions of lipids-in-water, and then treatment with ultrasonic, homogenization, microflow ejection, squeezing filtration, etc. The limposomes have improving statability, permeability and hydrophilic property, and can be used in preparation of drugs and cosmetics, especially transdermal delivery systems.
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